Human somatotropin: biological characterization of the recombinant molecule.

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Human somatotropin: biological characterization of the recombinant molecule.

The recombinant hormone obtained by non-covalent interaction of the NH2-terminal 134 amino acid fragment with the COOH-terminal 51 amino acid fragment of the reduced-carbamidomethylated human somatotropin molecule is found to exhibit nearly full biological activity of the native hormone, as evidenced by the stimulation of hepatic ornithine decarboxylase (L-ornithine carboxy-lyase, EC 4.1.1.17) ...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1976

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.73.10.3463